BIOLOGIJA SA HUMANOM GENETIKOM

After completing one-semester teaching and passing the Biology with Human Genetics exam, a student of Pharmacy will be able to: 1. Describe the structure and function of the hereditary basis of human: nucleic acids, replication, translation and transcription mechanisms, enzymatic regulatory systems, genetic code, chromosome organization, control of gene expression and genetic basis of reproduction; 2. Defines mechanisms for the generation of mutations and their impact on human health, as well as mechanisms for correcting errors in hereditary material; 3. defines the rules of inheritance and describes individual groups of hereditary diseases (chromosomal, monogenic, polygenic) and their behavior on the health of man and his offspring; 4. defines basic cytogenetic methods of cell culture, preparation of karyotype and analyzes the human karyotype using a light microscope; 5. Describes the basic methods of molecular genetics: isolation of DNA, PCR, endonucleases, a gel electrophoresis. 6. describes the application of modern cytogenetic and molecular-genetic techniques in the diagnosis and treatment of hereditary disorders.