OSNOVI MOLEKULARNE GENETIKE

After completing the course of molecular genetics in medical research PhD student of medicine and dentistry will be able to: 1. describe and explain the basic principles of molecular genetics, enzyme and gene regulatory systems and epigenetic mechanisms controlling gene expression; 2 define the mechanisms of mutations and repair mechanisms of mutation and design a basic model of research on mutations and their impact on human health; 3. explain the procedures and methods in molecular genetics that are used for analysis and identification of mutations in the human genome; 4. anticipate the importance of genetic research in certain high-risk populations and explain the importance of different research models in medical and molecular genetics; 5. use the relevant literature, databases and professional sites (OMIM, LDDB, POSSUM, ORPHANET); 6. place and set up certain medical-genetic problem and present the results of previous studies and plans to study this issue; 7. recognize bioethical risks and apply bioethical principles in the collection and handling of genetic data and knows how to protect the confidentiality of genetic data in accordance with bioethical principles.